Photo by Fabrice Récalt
Hotels in Guadalupe
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Mucumbli Hotel
Mucumbli Hotel
3.0 star property
Neves
9.4 out of 10, Exceptional, (26)
9.4/10
Exceptional
(26)
$131 nightly
The price is $153
$153 total
Jan 10 - Jan 11, 2026
Total with taxes and fees
Guest House Quinta Natural
Guest House Quinta Natural
3.0 star property
Trindade
10.0 out of 10, Exceptional, (1)
10/10
Exceptional
(1)
Praia Accommodation
Praia Accommodation
3.0 star property
São Tomé
7.2 out of 10, Good, (17)
7.2/10
Good
(17)
$127 nightly
The price is $146
$146 total
Dec 23 - Dec 24
Total with taxes and fees
Omali São Tomé – Principe Collection
Omali São Tomé – Principe Collection
4.0 star property
São Tomé
9.4 out of 10, Exceptional, (62)
9.4/10
Exceptional
(62)
$204 nightly
The price is $237
$237 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
Hotel Kenito
Hotel Kenito
2.5 star property
São Tomé
10.0 out of 10, Exceptional, (3)
10/10
Exceptional
(3)
$89 nightly
The price is $103
$103 total
Dec 23 - Dec 24
Total with taxes and fees
Hotel Praia
Hotel Praia
3.5 star property
São Tomé
7.6 out of 10, Good, (17)
7.6/10
Good
(17)
$153 nightly
The price is $179
$179 total
Dec 23 - Dec 24
Total with taxes and fees
Hotel Central
Hotel Central
3.5 star property
São Tomé
8.2 out of 10, Very Good, (24)
8.2/10
Very Good
(24)
SH Boutique Hotel
SH Boutique Hotel
3.5 star property
São Tomé
8.6 out of 10, Excellent, (10)
8.6/10
Excellent
(10)
Casa de Ferias
Casa de Ferias
3.0 star property
São Tomé
8.8 out of 10, Excellent, (6)
8.8/10
Excellent
(6)
$66 nightly
The price is $76
$76 total
Dec 23 - Dec 24
Total with taxes and fees
Pestana São Tomé
Pestana São Tomé
5.0 star property
Vila Maria
8.0 out of 10, Very Good, (78)
8.0/10
Very Good
(78)
$195 nightly
The price is $224
$224 total
Dec 26 - Dec 27
Total with taxes and fees
Alojamento Santos Silva
Alojamento Santos Silva
3.0 star property
São Tomé
$306 nightly
The price is $355
$355 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
CAMPISMO PRAIA GRANDE
CAMPISMO PRAIA GRANDE
1.0 star property
Malanza
8.6 out of 10, Excellent, (4)
8.6/10
Excellent
(4)
$52 nightly
The price is $61
$61 total
Dec 23 - Dec 24
Total with taxes and fees
Pestana Miramar São Tomé
Pestana Miramar São Tomé
3.0 star property
São Tomé
7.2 out of 10, Good, (45)
7.2/10
Good
(45)
$150 nightly
The price is $172
$172 total
Dec 23 - Dec 24
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Budget hotels in Guadalupe and vicinity
8.8 out of 10, Excellent, (6)
8.8/10
Excellent
(6)
$66 nightly
The price is $76
$76 total
Dec 23 - Dec 24
Total with taxes and fees
8.6 out of 10, Excellent, (4)
8.6/10
Excellent
(4)
$52 nightly
The price is $61
$61 total
Dec 23 - Dec 24
Total with taxes and fees
8.2 out of 10, Very Good, (24)
8.2/10
Very Good
(24)
10.0 out of 10, Exceptional, (1)
10/10
Exceptional
(1)
8.6 out of 10, Excellent, (10)
8.6/10
Excellent
(10)
10.0 out of 10, Exceptional, (3)
10/10
Exceptional
(3)
$89 nightly
The price is $103
$103 total
Dec 23 - Dec 24
Total with taxes and fees
7.2 out of 10, Good, (45)
7.2/10
Good
(45)
$150 nightly
The price is $172
$172 total
Dec 23 - Dec 24
Total with taxes and fees
7.2 out of 10, Good, (17)
7.2/10
Good
(17)
$127 nightly
The price is $146
$146 total
Dec 23 - Dec 24
Total with taxes and fees
9.4 out of 10, Exceptional, (26)
9.4/10
Exceptional
(26)
$131 nightly
The price is $153
$153 total
Jan 10 - Jan 11, 2026
Total with taxes and fees
7.6 out of 10, Good, (17)
7.6/10
Good
(17)
$153 nightly
The price is $179
$179 total
Dec 23 - Dec 24
Total with taxes and fees
8.0 out of 10, Very Good, (78)
8.0/10
Very Good
(78)
$195 nightly
The price is $224
$224 total
Dec 26 - Dec 27
Total with taxes and fees
9.4 out of 10, Exceptional, (62)
9.4/10
Exceptional
(62)
$204 nightly
The price is $237
$237 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Guadalupe
Learn more about Guadalupe
The region around Guadalupe is home to attractions such as São Sebastião Museum and Estadio Nacional 12 de Julho.
Photo by Fabrice Récalt
Open Photo by Fabrice Récalt
Check out reviews of Guadalupe hotels guests love
Pestana São Tomé
10/10 Excellent
"Wonderful stay, great staff, easy, relaxing delightful."
Omali São Tomé – Principe Collection
10/10 Excellent
"Staff was very friendly. Food was excellent. Room was clean and well kept."
Hotel Kriola
10/10 Excellent
"Loved the mermaids in the pool"
Porcelana Hotel
10/10 Excellent
"The place is great, water flows very well and you can get warm for your shower real quick. The hotel manager Leu was helpful and addressed any concerns I had. Again Sipson Tours was great with helping me navigate my accommodation. There is breakfast included and my best part is the fruit options which always part of the meal. The downside is that there is really no variety in the breakfast meal. However, overall I enjoyed my stay. "
Hotel Kenito
10/10 Excellent
"Exceptional"
CAMPISMO PRAIA GRANDE
10/10 Excellent
"A little piece of paradise on an amazing beach. "
Casa de Ferias
10/10 Excellent
"It's basic, but it's the best value on sao tome"
Frequently asked questions
How much does a hotel room cost in Guadalupe?
You can choose a great hotel in Guadalupe from $61 with properties to suit all budgets and needs. To find an affordable hotel in Guadalupe that meets all of your requirements, just apply filters on Hotels.com and sort hotels by "Price: low to high".
How can I find deals and earn rewards at Guadalupe hotels?
Discover great deals on Guadalupe hotel stays with Hotels.com. Take a look at hotel prices mid-week or during the low season as to find those off-peak deals. If you're up for a spontaneous trip, don't forget to check out our last-minute deals on Guadalupe hotels.
Can I book Guadalupe hotels with free cancellation?
In order to book a refundable Guadalupe hotel, simply filter hotels by "Property cancellation options" and select "Fully refundable property". Many hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are some popular hotels in central Guadalupe?
If you're looking for hotels in central Guadalupe, check out Mucumbli Hotel. Travelers love Mucumbli Hotel for its location, as well as the restaurant, bar/lounge and free parking this hotel offers.
What accommodations do travelers like in Guadalupe?
Guests like Residêncial Tamarindos, Pestana São Tomé and Hotel Central.
Can I book refundable hotels in Guadalupe?
If you need the flexibility to change your plans to Guadalupe, most properties provide refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.
Why should I book my Guadalupe hotel through Hotels.com?
There are lots of reasons to book your Guadalupe trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.