Business Hotels in Clayton

Free cancellation options if plans change
Unlock travel rewards with One Key
Save more with Member Prices

Check prices for these dates

Tonight
Apr 16 - Apr 17
Tomorrow
Apr 17 - Apr 18
This weekend
Apr 18 - Apr 20
Next weekend
Apr 25 - Apr 27

Business Hotels in Clayton

Clayton Plaza Hotel & Extended Stay
Exterior

Clayton Plaza Hotel & Extended Stay

3.5 star property
8.8 out of 10, Excellent, (2978)
The price is $116
includes taxes & fees
$100 per night
Apr 27 - Apr 28
Clayton Plaza Hotel & Extended Stay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in Clayton

Get a lay of the land and find the perfect place to stay
Downtown St. Louis showing signage, interior views and a bar

Downtown St. Louis

St. Louis's Downtown St. Louis neighborhood is known for its concert halls and museums, and entices visitors with attractions including Gateway Arch and Busch Stadium.

See properties in Downtown St. Louis
Downtown St. Louis

Top landmarks in Clayton

Busch Stadium

Busch Stadium

Why not catch an event at Busch Stadium, a major stadium in Downtown St. Louis. Our travelers also like the art galleries and museums in the area. If you think Busch Stadium is cool, you also might like Enterprise Center and Dome at America’s Center, both located nearby.

See properties in Busch Stadium
Busch Stadium

Frequently asked questions

What are the best business hotels in Clayton?
Based on guest reviews, The Lodge At Grant’s Trail is one of the top business hotels in Clayton. Make the most of a conference space and a free breakfast here. Four Seasons Hotel St Louis is also designed with business travelers in mind. It’s another visitor favorite.
What are the cheapest business hotels in Clayton?
Take your pick of cheap Clayton business hotels that work with your budget. Check out Hampton Inn & Suites St. Louis at Forest Park, which features a 24-hour front desk and a 24-hour business center. Another top choice for professionals on a budget is Hampton Inn St. Louis-Downtown (At the Gateway Arch).
What is the best time to stay in a business hotel in Clayton?
July is the warmest month, with temperatures ranging from 70ºF (21ºC) to 88ºF (31ºC). If you like cooler weather, organize your work trip for January. It’s generally between 25ºF (-4ºC) and 37ºF (3ºC) at this time. January is a good month to experience a more relaxed vibe and potentially lock in cheaper business hotels in Clayton.
What are the closest business hotels to Chapel of St. Timothy And St. Titus, Concordia Seminary?
Seal those deals at your business hotel in Clayton and then head out to explore Chapel of St. Timothy And St. Titus, Concordia Seminary. The Charles F. Knight Center is near this attraction and comes with a cafe and buffet breakfasts. Or, hit those deadlines and then take in the sights from Moonrise Hotel. It’s another stay that’s only a short drive away.
What business hotels in Clayton have a pool?
Four Seasons Hotel St Louis is a sought-after Clayton business hotel with a pool. Plus, you’ll have access to a cafe and an electric car charging station during your stay. For more options where you can take your work to the pool, look up Drury Plaza Hotel St. Louis at the Arch.
What are the closest business hotels to Lambert-St. Louis Intl. Airport (STL)?
Drury Inn & Suites St. Louis Airport is around 1 mile southeast of Lambert-St. Louis Intl. Airport (STL). Make the most of a swimming pool and free long-distance calls here. Wingate by Wyndham St. Louis Airport is another property that’s just a short drive away and perfect for traveling professionals. No long rides, no waiting around — choose one of the business hotels in Clayton near the airport and stay focused from the get-go.
What are the best 5-star business hotels in Clayton?
Four Seasons Hotel St Louis promises sophisticated surroundings for your next client meeting. This 5-star Clayton business hotel features a cafe and a swimming pool. Alternatively, get the VIP treatment on your business trip at The Ritz-Carlton, St. Louis.
Are there any business hotels in Clayton with parking?
Navigate your work trip effortlessly by staying at The Lodge at Grant’s Trail. This property comes with parking, a conference space and a free breakfast. Four Seasons Hotel St Louis is another stay that includes a space to leave your ride. If you’d like to see alternatives, browse the 1,823 Clayton business hotels with parking.