Hotels near Saint Francis Healthcare System Cape Girardeau

Free cancellation options if plans change
Unlock travel rewards with One Key
Save more with Member Prices

Check prices for these dates

Tonight
Apr 23 - Apr 24
Tomorrow
Apr 24 - Apr 25
This weekend
Apr 25 - Apr 27
Next weekend
May 2 - May 4

Where to stay near Saint Francis Healthcare System?

Drury Plaza Hotel Cape Girardeau Conference Center
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1001)
The price is $107
includes taxes & fees
$94 per night
Apr 27 - Apr 28
Drury Plaza Hotel Cape Girardeau Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other landmarks in Cape Girardeau

Cape Splash Family Aquatic Center

Bring the family to Cape Splash Family Aquatic Center and enjoy this exciting amusement park in Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

See properties in Cape Splash Family Aquatic Center
Cape Splash Family Aquatic Center
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
Sign in or join for free

Frequently asked questions

What are the best hotels near Saint Francis Healthcare System?
How much does it cost to stay in a hotel near Saint Francis Healthcare System?
Find the best options on Hotels.com for your travel budget by entering your search criteria and sorting by price. Pricing varies based on where you plan to go and when.
  • Search for the lowest price per night $66
What cheap hotels are close to Saint Francis Healthcare System?
  • For an economical hotel close to Saint Francis Healthcare System, consider Quality Inn, which offers a free English breakfast, free RV/bus/truck parking, and free in-room WiFi.
  • Another low-cost alternative is Tru By Hilton Cape Girardeau, which is 3 minutes away by car.
Can I find hotels close to Saint Francis Healthcare System that are fully refundable?
Yes, many hotels offer refundable room reservations if you cancel prior to the cancellation deadline. Find refundable rates using the “Fully refundable” filter when you search for hotels.
What are the best hotels close to Saint Francis Healthcare System with free breakfast?
  • You can enjoy a free English breakfast at Quality Inn, which is a 13-minute walk from Saint Francis Healthcare System.
  • Tru By Hilton Cape Girardeau, also recommended, is 3 minutes away by car and offers free breakfast.
Which hotels near Saint Francis Healthcare System have rooms with great views?
What are the best family hotels close to Saint Francis Healthcare System?
What are the best hotels near Saint Francis Healthcare System with free parking?
  • Drive and park with ease when you stay at Quality Inn, which offers free parking. You’ll be a 13-minute walk from Saint Francis Healthcare System.
  • Another property that offers free parking is Town House Inn Cape Giradreau, which is 3 minutes away by car.
What are the best hotels near Saint Francis Healthcare System with a pool?
What cheap motels can I book close to Saint Francis Healthcare System?
  • To stay economically near Saint Francis Healthcare System, you can book Town House Inn Cape Giradreau, which offers parking and free in-room WiFi.
What are the best things to see and do around my hotel near Saint Francis Healthcare System?
  • You may also want to see sights near Saint Francis Healthcare System like Giant City State Park, Southeast Missouri State University, and Isle Casino Cape Girardeau.
  • Show Me Center and Stone Creek Golf Club and Resort are other places to visit in the area.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

https://www.hotels.com/lp/b/deals