Hotels in East Prairie

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Check prices for these dates

Tonight
Apr 18 - Apr 19
Tomorrow
Apr 19 - Apr 20
This weekend
Apr 18 - Apr 20
Next weekend
Apr 25 - Apr 27

Where to stay in East Prairie?

Quality Inn Charleston - Sikeston
Desk, laptop workspace, blackout drapes, iron/ironing board

Quality Inn Charleston - Sikeston

2.5 star property
6.8 out of 10, (376)
The price is $79
includes taxes & fees
$71 per night
May 18 - May 19
Quality Inn Charleston - Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in East Prairie

Big Oak Tree State Park

Big Oak Tree State Park is 10.3 mi (16.6 km) from central East Prairie, why not stop by during your stay.

See properties in Big Oak Tree State Park
Big Oak Tree State Park

Learn more about East Prairie

East Prairie is well-known for its attractions such as Big Oak Tree State Park and Mississippi River.

See all hotels in East Prairie

Frequently asked questions

What hotels do travelers like in East Prairie?
Guests like Quality Inn Charleston - Sikeston.
Can I book a refundable hotel in East Prairie?
If you need the flexibility to change your travel plans to East Prairie, most hotels provide refundable* rates you can book. You can find these properties by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in East Prairie be like during my trip?
July and August are typically the warmest months in East Prairie when the average temp is 77°F. January and February are the coldest months when the average temperature is 41°F. March and April are the months with the most rain.
Why should I book my East Prairie accommodation with Hotels.com?
There are lots of reasons to book your East Prairie trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.