Photo by Jeff White

Hotels in Adrian

Free cancellation options if plans change
Unlock travel rewards with One Key
Save more with Member Prices

Check prices for these dates

Tonight
Jun 7 - Jun 8
Tomorrow
Jun 8 - Jun 9
Next weekend
Jun 13 - Jun 15
In two weeks
Jun 20 - Jun 22

Where to stay in Adrian?

Route 66 Inn & Suites by OYO Vega Tx
Exterior

Route 66 Inn & Suites by OYO Vega Tx

2.5 star property
7.8 out of 10, Good, (324)
$69 nightly
The price is $76
Jun 11 - Jun 12
Total includes taxes and fees
Route 66 Inn & Suites by OYO Vega Tx
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Adrian

Midway Point of Route 66

You might want to get your camera out and head to Midway Point of Route 66— just one of the landmarks located 0.5 mi (0.8 km) from central Adrian.

See properties in Midway Point of Route 66
Midway Point of Route 66

Learn more about Adrian

The region around Adrian is home to attractions such as Midway Point of Route 66 and Magnolia Gas Station.

See all hotels in Adrian
Adrian is just off Interstate 40. It is also the midpoint of the historic Route 66. From here it is 1139 miles East to Chicago and 1139 miles West to Los Angeles. There is also Midpoint Cafe, a 50's style diner with a great burger and fries. However, if you stop you have to ask about their "Ugly Pie."
Photo by Jeff White
Open Photo by Jeff White

Frequently asked questions

Can I book refundable hotels in Adrian?
If you want the flexibility to change your travel plans to Adrian, most hotels provide refundable* rates you can book. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in Adrian be like during my trip?
The warmest months in Adrian are usually July and August with an average temp of 78°F. January and December are the chilliest months when the average temp is 43°F. The rainiest months are May and October.
Why should I book my Adrian hotel through Hotels.com?
There are plenty of reasons to book your Adrian travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Adrian

Find out more about Adrian

If you're looking to discover somewhere new, look no further than Adrian. Whether you're planning to stay for a night or for the week, the area around Adrian has accommodations to fit every need. Search for hotels in Adrian with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Adrian hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Adrian hotel deals are here with our lowest price guarantee.